Ting-Huei Chen
Professeure adjointe au Département de mathématiques et de statistique de l'Université Laval
Pavillon Alexandre Vachon, bureau 2213
Téléphone: 418-656-2131, poste 3695
Courriel: ting-huei.chen@mat.ulaval.ca

Membre du centre de recherches mathématiques (CRM) ainsi que du laboratoire de statistique du CRM


Prospective students
I have projects for master students and summer projects for undergraduates. Please contact me if you are interested.

Publications
  • Wright F., Sullivan P., Brooks A., Zou F., Sun W., Xia K., Madar V., Abdellaoui A., Batista S., Butler C., Chen G., Chen T.-H., Chung W., D'Ambrosio D., de Geus E., Gallins P., Ha M., Hottenga J., Huang S., Jansen R., Kattenberg M., Kochar J., Middeldorp C., Qu A., Shabalin A., Smit J., Tisch eld J., Todd L., Tzeng J., van Grootheest G., Vink J., Wang Q., Wang W., Wang W., Willemsen G., Yin Z., Zhou Y., Penninx B., Boomsma D. "Heritability and Genomics of Gene Expression," (2014) Nature Genetics, 46(5), 430-437.
  • Sun W., Liu Y., Crowley J., Chen T.-H., Zhou H., Chu H., Huang S., Kuan P., Li Y., Miller D., Shaw G., Wu Y., Zhabotynsky V., McMillan L., Zou F., Sullivan P., and Pardo- Manuel de Villena F., "IsoDOT Detects Di erential RNA-isoform Usage with respect to a Categorical or Continuous Covariate with High Sensitivity and Speci city," (2015) Journal of the American Statistical Association, 110 (511) 975-986.
  • Chen T.-H. , Sun W. and Fine J. "Designing Penalty Functions in High Dimensional Problems: The Role of Tuning Parameters.,"(2016) Electronic Journal of Statistics 10(2): 2312-2328.
  • Chen T.-H. and Sun W. "Prediction of Cancer Drugs' Sensitivities Using High-dimensional Genomic Features," (2016) Biostatistics. 18(1): 1-14.
  • Arterberry BJ, Chen T.-H., Vergs A, Bollen KA, Martens MP."How Should Alcohol Problems Be Conceptualized? Causal Indicators within the Rutgers Alcohol Problem Index," (2016) Evaluation & the Health Professions. 39(3): 356-378.
  • Sharma V, Collins LB, Chen T.-H. , Herr N, Takeda S, Sun W, Swenberg JA, Nakamura J. "Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations," (2016) Oncotarget. 7(18): 25377-25390.
  • Roque D., Makowski L., Chen T.-H., Rashid N., Hayes N., Bae-Jump V., "Association between dierential gene expression and body mass index among endometrial cancers from The Cancer Genome Atlas Project,"(2016) Gynecologic oncology. 142(2): 317-322.
  • Wei Sun*, Katerina Kechris*, Sean Jacobson*, Gregory A. Hawkins, Jenny Yang, Ting-huei Chen, Pedro Miguel Quibrera, Wayne Anderson, R. Graham Barr, Patricia V. Basta, Eu- gene R. Bleecker, Terri Beaty, Richard Casaburi, Peter Castaldi, Michael H. Cho, Alejandro Comellas, James Crapo, Gerard Criner, Dawn Demeo, Stephanie A. Christenson, David J.Couper, Jeffrey L. Curtis, Claire M. Doerschuk, M. Bradley Drummond, Christine M. Freeman, Natalia A. Gouskova, MeiLan K. Han, Nicola A. Hanania, Nadia N. Hansel, Craig P. Hersh, Eric A. Homan, Robert J. Kaner, Richard E. Kanner, Eric C. Kleerup, Sharon Lutz, Fernando J. Martinez, Deborah A. Meyers, Stephen P. Peters, Elizabeth Regan, Stephen I. Rennard, Mary Beth Scholand, Edwin K. Silverman, Prescott G. Woodruff, Wanda K. O'Neal, Russell P.Bowler for the SPIROMICS Research Group and COPDGene Investigators. (2016). "Common Genetic Polymorphisms Infuence Blood Biomarker Associations in COPD," PLOS Genetics. 12(8).
  • Lindsay M. Morton*, Joshua N. Sampson*, Gregory T. Armstrong*, Ting-Huei Chen, Melissa Hudson, Eric Karlins, Casey L. Dagnall, Shenchao Li, Carmen L. Wilson, Kumar Sri- vastava, Wei Liu, Guolian Kang, Kevin Oenger, Tara O. Henderson, Chaya S. Moskowitz, Todd M. Gibson, Diana M. Merino, Jeannette R. Wong, Sue Hammond, Joseph P. Neglia, Lucie M. Turcotte, Jeremy Miller, Laura Bowen, William A. Wheeler, Wendy M. Leisen- ring, John A. Whitton, Laurie Burdette, Belynda D. Hicks, Mitchell J. Machiela, Aurelie Vogt, Zhaoming Wang, Meredith Yeager, Georey Neale, Matthew Lear, Louise C. Strong, Yutaka Yasui, Marilyn Stovall, Rita E. Weathers, Susan A. Smith, Rebecca Howell, Stella M. Davies, Gretchen A. Radloff, Amy Berrington de Gonzlez, Peter D. Inskip, Preetha Rajaraman, Joseph F. Fraumeni, Smita Bhatia, Stephen J. Chanock, Margaret A. Tucker and Leslie L. Robison. (2017) "Genome-wide association study identifies two susceptibility loci that modify radiation-related risk for breast cancer after childhood cancer: A report from the Childhood Cancer Survivor Study and St. Jude Lifetime Cohort," accepted for Journal of the National Cancer Institute.



    Enseignement
  • Hiver 2016, Introduction à la statistique génétique
  • Automne 2016, Modèles d'équations structurelles
  • Hiver 2017, Analyse de tableaux de fréquences
  • Hiver 2017, Statistique computationnelle

    Projets en cours
  • Ting-Huei Chen. "Multiple Loci Association Mapping for Latent Biological Traits in Complex Diseases Using a Structural Equation Modeling Approach with Application in Alzheimer's Disease."
  • Ting-Huei Chen and Jason P. Fine "Adaptive estimation of partially identi able parametric models."
  • Ting-Huei Chen, Jianxin Shi, Nilanjan Chatterjee "A polygenic risk modeling technique to incorporate linkage disequilibrium and functional information of SNPs using genome-wide association study summary-level data" 2017 August JSM presentation.
  • Andriy Derkach, Joshua Sampson, Ting-Huei Chen, Ruth Pfeiffer, "High Dimensional Mediation Analysis with Latent Factors." 2017 March ENAR presentation.
  • Using genome-wide information to find the best strategy of melanoma risk prediction.